Deflazacort

What is it?

Composition

The main component of Deflazacort is deflazacort itself, the active ingredient. It is used to regulate and reduce inflammatory processes in the body. The drug contains the following ingredients:

• Active ingredient: deflazacort
• Inactive ingredients, which may vary depending on the manufacturer: lactose, magnesium stearate, gelatin, and starch.
• Various tablet strengths to ensure precise dosing.

It is important to note that the composition may vary depending on the specific pharmaceutical company manufacturing the drug. Therefore, it is always important to carefully read the full composition before using it, especially if you have an allergic reaction to any of the ingredients. Alternative ingredients, such as starch and gelatin, help ensure the stability and effectiveness of the formula and also play an important role in the manufacturing process.

How to use?

When using Deflazacort, its important to strictly follow your doctors instructions regarding dosage and administration schedule. Initiating treatment requires precision, and the medication can be taken with or without food.

1. It is recommended to take the medication according to your doctors recommendations, who will determine the exact dosage based on the patients weight, especially for children and adolescents.
2. The dosage for adults is typically approximately 0.9 mg/kg, taken once daily. A similar dosage is also used for children over two years of age, with maximum accuracy in calculations and recommendations.
3. Please remember that the dosage may need to be adjusted based on changes in body weight and should also be regularly assessed based on the patients clinical condition.

Adjusting or skipping doses on your own may negatively impact treatment, so consulting a doctor is essential with any questions or concerns.

How does it work?

Deflazacorts mechanism of action is based on its ability to reduce inflammation by inhibiting the synthesis of certain proteins involved in the inflammatory response. This steroid helps alleviate the symptoms of Duchenne muscular dystrophy by stabilizing cell membranes and suppressing immune system activity, ultimately slowing degenerative muscle changes.

As a result, patients may experience improved overall muscle strength and performance, which can reduce long-term disability. While Deflazacort does not cure the disease itself, it provides significant support in managing its symptoms. This allows patients to lead a more active lifestyle and maintain a certain level of physical activity. However, its effectiveness may vary depending on individual characteristics and the progression of the disease.

Indications

Deflazacort is indicated for use in patients with Duchenne muscular dystrophy. Its use is highly specific due to the rarity and motor complexity of this disease. The drug helps improve the quality of life of patients suffering from this severe pathology.

• Duchenne muscular dystrophy in children over two years of age and adults
• Need to improve muscle strength
• Slowing the progression of muscle disability

Furthermore, Deflazacort is prescribed in situations where standard therapy has proven ineffective in controlling symptoms or when alternative treatments are unavailable. The drug is often prescribed only under the supervision of a specialist, who will weigh all the possible risks and benefits of treatment.

Contraindications

Contraindications to the use of Deflazacort are quite serious and require a thorough review of the patients medical history and current health status. Some conditions may be significantly worsened by the drug, so it is important to discuss potential risks with a doctor beforehand.

• Allergy or hypersensitivity to Deflazacort or its components
• Use in children under two years of age
• Consumption of grapefruit or grapefruit juice during treatment
• Receipt of live vaccines within a certain time before and after use of the drug

The use of Deflazacort always requires medical consultation, especially if the patient is prone to allergies or is experiencing an exacerbation of chronic diseases. A specialist should be informed of all current and previous health conditions to reduce the risk of complications.

Side effects

Deflazacort use may be associated with a number of side effects, ranging from mild to serious. Each patient is unique, and their response to the drug may vary, so it is important to carefully monitor any changes and report them to your doctor if necessary.

• Increased blood pressure and heart disease
• Blood sugar imbalances, requiring monitoring in patients with diabetes
• Digestive problems, including nausea and vomiting
• Weight gain and fluid retention
• Changes in behavior and mood, such as irritability and depression

In most cases, side effects can be controlled or minimized by adjusting the dose or making diet and lifestyle changes. However, if alarming symptoms such as difficulty breathing or severe allergic reactions occur, immediate medical attention is required.